Affiliated School or College: School of Medicine
The Mouse Behavioral Phenotyping Core (MBPC) performs behavioral testing on murine disease models to assay motor, learning, emotional and social phenotypes that may be present. We offer a wide variety of behavioral equipment options in one convenient location within the HSAF. The core is available to self-service users after training; and it offers full-service experimental services to clients from ºÚÁϳԹÏÍø and surrounding institutions.
The goal of the MBPC is to provide a convenient resource for investigators at ºÚÁϳԹÏÍø and other nearby institutions, to produce in-depth characterization of mouse behaviors with state of the art mouse behavioral testing. The core facility is equipped to perform a comprehensive battery of behavioral tests to thoroughly phenotype overall motor and sensory function of mice, as well as phenotype specific behaviors that are of interest to the investigators (learning and memory, place/fear conditioning, pain/analgesia, anxiety-related, depression-related behaviors, and various social behaviors).
Recent publications from the core:
- Ellit, Matthew. "Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease." Nature. 2020 Jul 1;585(7825):397-403.
- Wang, Wenzhang. "Space-Like Irradiation Exacerbated Cognitive Deficits and Amyloid Pathology in CRND8 Mouse Model of Alzheimer's Disease." J Alzheimers Dis. 2024; 100(s1):S327-S339
- Mast, Natalia. "7,8-Dihydroxy Efavirenz Is Not as Effective in CYP46A1 Activation In Vivo as Efavirenz or Its 8,14-Dihydroxy Metabolite." Int J Mol Sci. 2024 Feb13;25(4):2242
Customers: External and Internal
Hours
24/7