ºÚÁϳԹÏÍø

The objective of the Tissue Resources Core is to collect, prepare and distribute high-quality human tissue samples (including solid tissues, blood and other biospecimens) to researchers located on the ºÚÁϳԹÏÍø and University Hospitals Cleveland Medical Center (UHCMC) campuses and others that have professional appointments with UHCMC or ºÚÁϳԹÏÍø, and to organized tissue procurement networks such as the CHTN.

In order to serve the greater research community, underutilized tissue resources will also be provided to external academic and commercial researchers conducting basic and applied medical research. Remnant tissue specimens will be prospectively obtained from surgeries and autopsies at UHCMC and possibly other participating collection sites. The samples will be obtained from tissues that would otherwise be discarded following examination by the assigned surgical pathologist. The surgical procedure is not altered in any way to obtain tissue for research purposes. Normal, benign, diseased, precancerous and cancerous tissue will be collected from a wide variety of organ sites to fulfill active tissue requests. Rare tumors that are not currently being requested may also be collected if a future need is anticipated. Specimens are prepared according to researchers’ specific requirements and may be fresh, frozen, fixed or in block or slide form.

The facility operates primarily as a prospective service, so most of the tissues are not pre-existing at the time the tissue request is submitted. Some samples are stored in a biorepository for eventual assignment to researchers in future studies. The Tissue Resources Core also specializes in and provides services for routine and advanced histology, simplex and multiplex immunohistochemistry, in situ hybridization, tissue microarray, and digital photomicroscopy.

Learn more about the Tissue Resources Core

Organization Affiliations: Case Comprehensive Cancer Center, Ohio State University, Cooperative Human Tissue Network (CHTN)